Capecitabine + Epirubicin + Cyclophosphamide Combination Therapy (CEX Therapy) as Neoadjuvant Chemotherapy for HER-2-Negative Breast Cancer: A Retrospective, Single-Center Study
نویسندگان
چکیده
منابع مشابه
The combination of epirubicin plus docetaxel as neoadjuvant chemotherapy in locally-advanced breast cancer.
BACKGROUND The purpose of this study was to evaluate the activity and toxicity of epirubicin plus docetaxel as neoadjuvant chemotherapy for locally advanced breast cancer. PATIENTS AND METHODS In this single-center, phase II trial, twenty-one patients with locally advanced breast cancer (T>3 cm or N>1) received epirubicin (70 mg/m2) and docetaxel (60 mg/m2) on Day 1 of each cycle for up to 6 ...
متن کاملCapecitabine-based combination therapy for breast cancer: implications for nurses.
PURPOSE/OBJECTIVES To review available data and implications for nurses of combination regimens containing capecitabine for metastatic breast cancer. DATA SOURCES Peer-reviewed publications or abstracts from major oncology conferences and reviews of capecitabine focusing on nursing implications. DATA SYNTHESIS Capecitabine has proven efficacy in combination with docetaxel and is under evalu...
متن کاملEpirubicin and cyclophosphamide, methotrexate, and fluorouracil as adjuvant therapy for early breast cancer.
BACKGROUND The National Epirubicin Adjuvant Trial (NEAT) and the BR9601 trial examined the efficacy of anthracyclines in the adjuvant treatment of early breast cancer. METHODS In NEAT, we compared four cycles of epirubicin followed by four cycles of cyclophosphamide, methotrexate, and fluorouracil (CMF) with six cycles of CMF alone. In the BR9601 trial, we compared four cycles of epirubicin f...
متن کاملCapecitabine maintenance therapy for XT chemotherapy-sensitive patients with metastatic triple-negative breast cancer.
OBJECTIVE To investigate the efficacy and safety of capecitabine maintenance therapy (MT) after initial capecitabine plus docetaxel (XT) chemotherapy in patients with metastatic triple-negative breast cancer (mTNBC). METHODS Fifty-five mTNBC patients treated with XT chemotherapy between May 2007 and June 2013 were retrospectively analyzed. When initial disease control was achieved by the comb...
متن کاملEfficacy of capecitabine-based combination therapy and single-agent capecitabine maintenance therapy in patients with metastatic breast cancer.
OBJECTIVE The purpose of this study was to observe the efficacy and toxicities of capecitabine-based chemotherapy and capecitabine monotherapy as maintenance therapy in the treatment of metastatic breast cancer (MBC). PATIENTS AND METHODS A total of 98 MBC patients were treated with capecitabine combined with vinorelbine (NX). RESULTS The median number of treatment was 6 cycles (1-7 cycles)...
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ژورنال
عنوان ژورنال: Journal of Nippon Medical School
سال: 2020
ISSN: 1345-4676,1347-3409
DOI: 10.1272/jnms.jnms.2020_87-204